Summary
Mostisekai stories are often set in fantasy worlds, particularly the ones that are frequently featured in role-playing games. Elves, monsters, and magic are frequent tropes common to these kinds of fantasy worlds, and while there’s nothing wrong with that, they can certainly get a little predictable.
Sometimes, isekai stories try for a little more than the usual norm and come up with a setting that’s a lot stranger than the usual fantasy. These isekai worlds might put interesting twists on the standard fantasy setting, or they might introduce a unique world with its quirks and idiosyncrasies.

At first glance,KonoSubalooks like it takes place in a fairly standard fantasy world. The majority of the series takes place in an adventurers' town, and the many monsters Kazuma and his party face are fairly standard enemies that can be found in most video games.
However, the main thing that makes the world ofKonoSubastand out from other fantasy worlds is the bizarre personalities many of its denizens have. Whether it be scam-happy cultists, bumbling demon generals, or petulant and spoiled goddesses,KonoSubaprovides a picture of a fantasy world that is very different from those of its contemporaries.

The world ofDriftersis a standard fantasy world, where elves, humans, and all kinds of fantasy creatures and monsters exist. It would be a fairly standard fantasy tale were it not for the Drifters, great figures from history who came to this world right before their deaths.
The Drifters' main enemies are the Ends, who are also great historical figures who forsook their humanity, allowing them to gain supernatural powers. The two factions come into conflict due to their opposing goals: the Ends wish to take over this new world for their own ends, while the Drifters seek to protect it.

Welcome to Demon School! Iruma-kunsees Iruma Suzuki taken from his normal life and sold to a demon in the Demon World. Though he initially fears for his life, he soon finds out that life in the Demon World is better than his life under his debt-ridden, money-hungry parents. He is soon enrolled in a school for demons, where he is told not to reveal the fact that he is really human.
The Demon World is certainly filled with plenty of threats and horrors,but it is also filled with plenty of friendly and silly demons as well. The demons also have quite a bizarre and flashy culture, featuring plenty of strange festivals and traditions that break from the usual demonic archetypes.

WhileDigimonhas never managed to reach the peaks thatPokemonhas, it has managed to establish itself a cult following as an alternative to the more popular franchise. Its prominence started with the originalDigimon Adventureanime,which laughed the franchise to stardom.
Digimon Adventuresees a group of children sent to the Digital World, a strange world that is similar to the real world but is constantly changing and adjusting due to the modification of data happening in the real world. The Digital World is also populated by Digimon, digital creatures that can evolve based on the level of their relationship with a human partner. While the Digital World constantly changes and morphs with each subsequent series, it remains incredibly unique in the realm of isekai.

No Game No Lifebrings legendary gamers Sora and Shiro to the world of Disboard,where every conflict is decided in a game rather than in war. The world is separated into sixteen different nations, with the conqueror of all sixteen granted the chance to challenge Tet, the god of Disboard.
After becoming the representatives of the human kingdom of Elkia, Sora and Shiro set out to compete against the other species to gain the right to challenge Tet. While they can only challenge each other by using games, cheating is allowed as long as it is not discovered, making it a viable tactic for those who are discreet enough.

6Tsubasa: Reservoir Chronicle
A Journey Through The World Of CLAMP
Tsubasa: Reservoir Chroniclefollows the adventures of Syaoran, Kurogane, and Fai, who adventure through different worlds as they try to find the feathers that make up Sakura’s memories and powers. Though they must sacrifice much and constantly struggle through various dimensions, the group persists in restoring Sakura to her full self.
Tsubasa: Reservoir Chroniclewas created from a desire to unitemany of CLAMP’s previous worksinto a unified world. The result is a story that goes through all kinds of interesting worlds, from standard fantasy to strange, mystical ones.

While traveling to their new home, Chihiro Ogino’s father decides to stop at a nearby abandoned park. They soon find they are unable to leave, and Chihiro’s parents turn into pigs, having eaten the food provided there. Without knowing it, the three have been transported to the world of spirits, and only Chihiro can get them out.
Spirited Awayisone of Studio Ghibli’s most famous movies, featuring a rich world full of bizarre and fantastical renditions of classic Japanese folktale creatures. The strange beings and existences that appear in the movie are some of the strangest in anime, making the world ofSpirited Awaya true wonder.